INSULINA LISPRO BULA PDF

aplicação de insulina em diabéticos.1 . *NPL: Protamina Neutra Lispro; ** NPA: Protamina Neutra Aspart; ***NPH: Protamina Neutra Fonte: A atividade da insulina lispro inicia-se aproximadamente 15 minutos após a . médico e leve a embalagem ou bula do medicamento, se possível. Ligue para. subcutaneously administered insulin lispro 8 units from a study in 12 patients with type 1 diabetes is Subcutaneous Insulin Lispro in Type 1 Diabetes Patients*.

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Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen

Breast-feeding Patients with diabetes who are breast-feeding may require adjustments in insulin dose, diet or both. Llispro may be given shortly before meals. Hepatic impairment Insulin requirements may be reduced in patients with hepatic impairment due to reduced capacity for gluconeogenesis and reduced insulin breakdown; however, in patients with chronic hepatic impairment, an increase in insulin resistance may lead to increased insulin requirements.

Use of injection sites should be rotated so that the same site is not used more than approximately once a month. Insulin requirements may be increased by medicinal products with hyperglycaemic activity, such as oral contraceptives, corticosteroids, or thyroid replacement therapy, danazol, beta 2 stimulants such as ritodrine, isnulina, terbutaline. The number of insulin units is shown in the dose window of the pen regardless of strength and no dose conversion should be done when transferring a patient to a new strength or to a pen with a different dose step.

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It is essential to maintain good control of the insulin-treated insulin-dependent or gestational diabetes patient throughout pregnancy. This information is intended for use by health professionals. Transferring a patient to another type or brand of insulin should be done under strict medical supervision.

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Redness, swelling, and itching can occur at the site of insulin injection. Each KwikPen delivers units in lisprl of 1 unit.

Glucodynamic differences between insulin lispro and soluble human insulin, as measured during a glucose clamp procedure, were maintained over a wide range of renal function. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia [see Warnings and Precautions Insulin who fail to respond to glucagon must be given glucose solution intravenously.

The reduction of HbA1c would also be expected with other insulin products e. Local allergy in patients is common. Sustained carbohydrate intake and observation may be necessary because hypoglycaemia may recur after apparent clinical recovery.

Hypoglycaemia may occur as a result of an excess of insulin activity relative to food intake and energy expenditure. Learn about Humalog Insulin Lispro Human Analog may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related For the full list of excipients, see section 6.

Back to top Eli Lilly and Company Limited contact details. New to Type 1 Diabetes? Pioglitazone should be discontinued, if any deterioration in cardiac symptoms occurs. In patients with type 2 diabetes on maximum doses of sulphonyl urea agents, studies have shown that the addition of insulin lispro significantly reduces HbA1c compared to sulphonyl urea alone.

The pharmacokinetics of insulin lispro reflect a compound that is rapidly absorbed, and achieves peak blood levels 30 to 70 minutes following subcutaneous injection. Time to maximum concentration was also similar between formulations. MedDRA system organ classes. It may cause a rash over the whole body, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating.

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Hipoglicemiante

The markings on the insulin syringe will not measure the dose correctly. Patients must be instructed to always check the insulin label before each injection to avoid accidental mix-ups between the two different strengths of Humalog as well as other insulin products. Insulin requirements usually fall during the insulinz trimester and increase during the second and third trimesters.

Method of administration Humalog solution for injection should be given subcutaneously. Clinical trials in patients with type 1 and type 2 diabetes have demonstrated reduced postprandial hyperglycaemia with insulin lispro compared to soluble human insulin.

Insulins have no specific overdose definitions because serum glucose concentrations are a hula of complex interactions between insulin levels, glucose availability and other metabolic processes. The KwikPen has to be used as recommended in the user manual.

Strengths Available for Humalog |

By continuing to browse the site you are agreeing to our policy on the use of cookies. View our Humalog coupons and manufacturer promo offers. Show table of contents Hide table of contents 1. Posology The dosage should be determined by the physician, according to the requirement of the patient. Do not expose to excessive heat or direct sunlight. Active ingredient insulin lispro. Exercise taken immediately after a meal may increase the risk of hypoglycaemia.

Insulin lispro maintains more rapid absorption when compared to soluble human insulin in patients with renal impairment.

The patient should be given a meal as soon as consciousness is recovered.